- Kidney stones
- Urine alkalinization
- Urinary Tract Infection
- Micturition
Mechanism of Action-
Disodium hydrogen citrate is metabolized to bicarbonates, which increase urinary pH by increasing the excretion of free bicarbonate ions, without producing systemic alkalosis when administered in recommended doses. A rise in urinary pH increases the solubility of cystine in the urine and the ionization of uric acid to more soluble urate ion. By maintaining an alkaline urine, the actual dissolution of uric acid stones may be accomplished.
Common side effect of the product includes:
The product is possible safe for most adults. There is no disadvantage associated with the product if taken under the recommended usage however Diarrhoea, Nausea, Vomiting, Tiredness, Frequent urge to urinate, stomach cramps and Flatulence can occur in some patients.
Do not use this product in the following conditions:
-
Renal failure
- Pregnancy and breast feeding
Disodium hydrogen citrate reduces the gastric acidity which can decrease the absorption of the following drugs:
-
Aspirin and other salicylates
- Lithium
- Quinidine
- Ritonavir
- Ciprofloxacin
- Moxifloxacin
- Doxycycline
- Tetracycline
- Ketoconazole
- Itraconazole