- Shigella infections
- Chronic bronchitis
- Bacterial sinusitis
- Salmonella infections
- Urinary tract infections
Mechanism of Action-
Cefixime binds with the penicillin binding protein present inside the bacteria thus inhibits the cell wall synthesis process and thus the autolytic enzymes such as autolysin mediates cell wall lysis.
Pharmacokinetics-
Absorption:
It is about 40-50% absorbed orally
Protein Binding:
It is 65% bound to plasma proteins
Metabolism:
It is metabolized in the liver
Excretion:
It is excreted via urine
- Stomach upset
- Diarrhoea
- Nausea
- Gas
- Headache
- Dizziness
- Contraindicated in people with hypersensitivity reaction.
- Clopidogrel
- Valproic acid
- Ascorbic acid
- Furosemide