ALTIDOR-CV

Cefixime 200 mg, Clavulanate 125 mg Tablets

10x6 (Blister) Rs 255

ALTODOR-CV

This composition consists of cefixime and clavulanic acid which works by stopping the growth of the bacteria.
Clavulanic acid enhances the activity of the cefixime against bacteria.

Cefixime is a cephalosporin antibiotic. It belongs to the third-generation antibiotic. It is highly stable and resistance to beta lactamase enzymes.
It causes the inhibition of mucopeptides synthesis which helps in the cell wall synthesis.

Clavulanic acid is a beta lactamase inhibitor. It prevents the antibiotics damage from the beta lactamase enzyme.

  • Respiratory tract infection
  • Urinary tract infection
  • Gonorrhoea
  • Otitis media
  • In bone joint Infections
  • Sinusitis

Mechanism of Action-

Cefixime inhibits the peptidoglycan which is responsible for bacterial cell wall cross linking and then synthesis.
Clavulanic acid contains beta lactamase ring which binds with beta lactamases and inactivate them.

Pharmacokinetics-

Cefixime-
It is absorbed orally
It is about 65% bound to serum proteins
It is metabolized in the liver
It is excreted via urine

Clavulanic acid-
It is absorbed orally
It is 25% bound to serum proteins
It is metabolized in the liver
It is excreted via feces
  • Nausea
  • Diarrhoea
  • Upper abdominal pain
  • Vomiting
  • Contraindicated in liver disorders
  • Contraindicated in renal impairment
  • Warfarin
  • 4-hydroxycoumarin