- Respiratory infections
- Genitourinary infection
- Sexually transmitted diseases
- Cervicitis
- Pelvic inflammatory diseases
- Tonsillitis
- Urethritis
Mechanism of Action-
Azithromycin binds to the 23S rRNA of the 50 ribosomal submit. It inhibits the bacterial protein synthesis by inhibiting the step of translocation and transcription.
Pharmacokinetics:
Absorption-
It is absorbed orally.
Protein Binding-
It is 7% bound to serum proteins
Metabolism-
It is metabolized in the liver
Excretion-
It is excreted via urine
- Nausea
- Vomiting
- Abdominal pain
- Loose stools
- Stomach upset
- Contraindicated in diarrhoea
- Contraindicated in myasthenia gravis
- Prednisone
- Doxycycline
- Aspirin
- Levothyroxine
- Acetaminophen
- Omeprazole