KETOVAR-DT

Ketorolac 10 mg

10X10 (ALU-ALU) Rs 65

KETOVAR-DTs

Ketorolac belongs to the non-steroidal anti-inflammatory drug. It is used as ophthalmic solution.
It exists in the racemic mixture and its S form shows analgesic activity.

  • Mild to moderate pain

Mechanism of Action-

  • Ketorolac inhibits the synthesis of prostaglandins by competitively acting on the enzyme cyclooxygenase-1. prostaglandins mediate inflammation and swelling.
  • ketorolac reduces the level of prostaglandins and then secondly it furthersinhibit prostaglandin synthesis.

Pharmacokinetics-

Absorption- It is rapidly absorbed
Protein Binding- It is 99% bound to plasma proteins
Metabolism- It is metabolized in the liver
Excretion- It is excreted via urine
  • Constipation
  • Diarrhoea
  • Rash
  • Dizziness
  • Nausea
  • Abdominal pain
  • Headache
  • Dyspepsia
  • Somnolence
  • Contraindicated in renal impairment
  • Contraindicated in people with known hypersensitivity
  • Contraindicated in people with peptic ulcer

cautions-

  • It is used cautiously in hepatic impairment it may cause liver toxicity
  • It is cautiously used in inflammatory bowel disease
  • Store it at room temperature