OFLOSAR 200


Each Tablet Contains:
Ofloxacin HCL USP 200 mg 10X10 (ALU-ALU) Rs 54

OFLOSAR 200

Ofloxacin belongs to the flouroquilone class and has antibacterial properties. It shows bactericidal activity against both gram-negative and gram-positive bacteria. It has 100 times more affinity towards the enzyme DNA gyrase.

  • Treatment of gonorrhoea
  • Syphilis
  • Cervicitis
  • Conjunctivitis
  • In bacterial infections
  • Community acquired anemia
  • Prostatis
  • Traveller’s diarrhoea

Mechanism of Action:

Ofloxacin inhibits the enzyme DNA gyrase which is responsible for supercoiling of the One strand of DNA to other during replication or known as transcription.

Pharmacokinetics:

Absorption- It is absorbed by oral route
Protein Binding- It is 32% bound to plasma proteins
Metabolism- It is metabolized in the liver
Excretion- It is excreted via urine
  • Nausea
  • Vomiting
  • Constipation
  • Gas
  • Vomiting
  • Cramps in the stomach
  • Changes in ability to taste food
  • Loss of appetite
  • Contraindicated in myasthenia gravis
  • Contraindicated in people with low blood sugar
  • Warfarin
  • Amiodarone
  • Quinidine
  • Sotalol
  • Dofetilide