SARCETAMOL-250


Each 5 ml contains:
Paracetamol IP 125 mg

60 ML Rs 36.55

SARCETAMOL-250

Paracetamol 125 mg Oral Suspension is a medicine used to relieve pain and to reduce fever. It is used to treat many conditions such as headache, body ache, toothache and common cold.

Paracetamol 125 mg Oral Suspension may be prescribed alone or in combination with another medicine. You should take it regularly as advised by your doctor. It is usually best taken with food otherwise it may upset your stomach. Do not take more or use it for longer than recommended.

  • Fever
  • Mild pain
  • Pain
  • Severe Pain
  • Minor aches and pains
  • Moderate Pain

Mechanism of Action-

Paracetamol belongs to non-steroidal anti-inflammatory drugs which inhibits cyclooxygenase. Paracetamol is a derivative of acetaminophen, or paracetamol, with the molecular formula glycine, N, N-diethyl-,4-(acetylamino)phenyl ester. Paracetamol is a weak inhibition of COX-1 and COX-2, further inhibiting prostaglandin synthesis.

Pharmacokinetics-

Paracetamol is also well orally absorbed and volume of distribution is 1.29 l/kg. Protein binding of paracetamol is very negligible. It is metabolised in liver mainly by CYP enzymes. Paracetamol is mainly excreted in urine with a half-life of 3.6 hours.
Common side effect of the product includes:
  • Stomach pain
  • Nausea
  • Vomiting
  • Stomach ulcers
Do not use paracetamol suspension in the following conditions:
  • Caloric undernutrition.
  • Severe renal impairment.
  • A condition where the body is unable to maintain adequate blood flow called shock.
  • Acetaminophen overdose.
  • Acute inflammation of the liver due to hepatitis C virus.
Following drugs may interact with the combination:
  • Acenocoumarol
  • Carbamazepine
  • Fosphenytoin
  • Lixisenatide
  • Phenytoin
  • Warfarin
  • Zidovudine