TRIPSAR


Each Tablet Contains:
Aceclofenac 100 MG
Trypsin-Chymotrypsin 5000 AU

15 Rs 150

TRIPSAR


This composition contains trypsin, chymotrypsin and Aceclofenac is used together to reduces pain and swelling associated with any of the disease. All of these works by the lowering the certain chemicals or substances that causes pain and inflammation in the body. The breakdown of proteins by theses enzymes or the process of digestion continuous in the stomach.

Trypsin is protease enzyme and is mainly concerned with the hydrolysis of proteins. It is extracted from the bovine and porcine pancreas. Trypsin undergoes catalytic mechanism and helps in the digestion of proteins
Trypsin exits in inactive form which is then converted to active form by enzyme trypsinogen.

Chymotrypsin is also a digestive enzyme which leads to the cleavage of the peptide bonds in the protein molecules. It works even in the absence of catalyst.

Aceclofenac is the analog of diclofenac. It is obtained by doing certain modifications in the Aceclofenac. It is better then diclofenac because of its gastrointestinal tolerability. It has high permeability to penetrate into the synovial membrane.

  • Osteoporosis
  • Rheumatoid arthritis
  • Pain
  • Spondylitis

Mechanism of Action-

Trypsin causes breakdown of peptides by hydrolysing reaction and convert proteins into amino acids which are known as building blocks.
Chymotrypsin broke down the peptide bonds by its nucleophilic attack on the carbonyl group and forms complex with substrate known as enzyme substrate complex.
Aceclofenac inhibits the cox-1 and cox-2 activity by inhibiting the arachidonic acid which is responsible for prostaglandin synthesis. It also interferes with the neutrophil adhesion with the endothelium.

  • Heartburns
  • Dizziness
  • Swelling
  • Rashes
  • Itching
  • Difficulty in breathing
  • Liver damage
  • Loss of appetite
  • Contraindicated in people with known allergy
  • Methimazole
  • Aspirin
  • Clopidogrel
  • Pilocarpine
  • Captopril