VARCOLD

This composition contains anti-allergic agents, painkillers and anti-pyretic agents that relives the symptoms of common cold. This also narrows the small blood vessels and provides relief from the congestion and stuffiness of the nose.
Caffeine decreases sleepiness caused by cetirizine.

Nimesulide belongs to the non-steroidal anti-inflammatory drug. It gives immediate relief from the pain and fever. It is commonly used in the treatment of acute pains. Nimesulide selectively acts on the Cox-2 enzymes and consists of basic sulphonamide structure.
Paracetamol is known as OTC (over the counter) drug. It is effectively reduces mild to moderate pain. It belongs to the analgesics. It is given in children to reduce fever and is used to lower temperature during immunization to child. Cetirizine belongs to the second-generation class of antihistaminic drugs. It is effective against various allergic reactions such as running nose, allergy, congestion of nose.
Phenylephrine is the alpha-1 agonist of adrenergic receptors and is used to treat hypotension or vasoconstriction & dilation of pupils. It is also used in the nasal preparations to provide relief from the congestion.
Caffeine is methylxanthine derivative and is used to provide relief from pain, respiratory difficulties associated with new born and reduce drowsiness